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Check Closely (1)modafinil will boost the amount or outcome of citalopram by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on. Citalopram twenty mg/day is the utmost proposed dose for individuals using CYP2C19 inhibitors as a result of threat of QT prolongation.Ferraro et al (1996) in the initial of a series of papers about m